Wednesday, March 18, 2020

Chanca Piedra and Coronavirus

As many of you know, I’ve been working on a new series of books on the effective rainforest medicinal plants I’ve used for over 20 years as a health practitioner and product formulator to treat many types of diseases and conditions.  I wanted to share with you some vital information on one of these remarkable plants I’ve long used for viruses in light of the current events about viral concerns.
In fact, I’m working on the medicinal plant guide book for this plant right now, but it won’t be available for at least a month. The plant is called Chanca Piedra (Phyllanthus niruri) and it’s currently available as an herbal supplement under various labels in the marketplace.

I’ve used chanca piedra for many years as an effective herbal antiviral. It’s been the subject of clinical research in humans to treat hepatitis B and C. It’s also been confirmed to be effective against several herpes viruses (including the chicken pox virus in children), HIV, influenza, dengue, and others.  It works by inhibiting enzymes and other substances that viruses need to divide and multiply (transcriptase and protease), while also providing a direct toxic effect to some viruses (as well as bacteria). Researchers have confirmed the presence of at least 8 natural plant chemicals in the plant with antiviral actions.  It has not been scientifically tested against this current coronavirus, however I used it effectively with several clients (including my own granddaughter) when the country was fighting the H1N1 swine flu virus years ago.

In addition to being a good antiviral, significant new research on chanca piedra confirms it is an effective immune modulator.  It significantly increases the production and activation of immune cells responsible for fighting infections, while lowering the production of immune cells that cause inflammation.  This has also been confirmed in human research.  In human trials, adults and children with pneumonia, tuberculosis, hepatitis, chicken pox, and Hanson's disease (leprosy) mounted a much stronger immune response to fight these infections which sped healing and viral/bacterial clearance.  It was also noted that immune cells responsible for immunity were also increased, and those taking chanca piedra for their infections had no relapses or secondary infections and had higher levels of antigens (cells responsible for immunity). The small trial on leprosy patients led researchers to surmise that it's strong and immediate immunity response might be helpful as a preventative/anti-infection remedy to protect caregivers of this devastating disease.

In the people with pneumonia, asthma, and tuberculosis that were studied, a significant reduction in lung inflammation was also noted with significantly less pro-inflammatory immune cells causing lung cell stress, damage and cell death. Chanca piedra’s many strong antioxidant plant chemicals were probably one reason for this noted effect.  However, other research has been published on chanca piedra’s effective anti-inflammatory actions delivered by other novel anti-inflammatory chemicals in the plant.

I don't know if chanca piedra can kill this particular coronavirus outright like it can other viruses. That it boosts the immune system to fight both bacterial and viral infections naturally, as well as protects the lungs from inflammation and cell damage bacteria and virus causes in the lungs was enough for me to stock up on chanca piedra to protect myself and family, just in case, during these trying times.  
If you want to get chanca piedra to have on hand, just in case, look for a supplement that uses chanca piedra that was harvested (preferably wild-harvested) in Peru or Brazil. Buy a whole-herb in bulk, capsules, or tablets and avoid the dry or liquid extracts that used alcohol to prepare them.  The active ingredients in chanca piedra are water soluble and don't much like alcohol.  Also there are other species of Phyllanthus plants being sold as “chanca piedra” harvested in China, India and Southeast Asia that are not as effective and don’t contain as many natural plant compounds as the South American Phyllanthus niruri species does (lots of research confirms this).  Personally, I purchase chanca piedra from Rainforest Pharmacy ( since they are wild-harvesting it from Peruvian rainforest. You can also get their product from

I’ve just uploaded all the new research on Chanca Piedra in my Tropical Plant Database at  so you can see all the new research conducted on this effective rainforest plant with many active chemicals and many medicinal uses.  Hopefully, the new rainforest medicinal plant guide book on chanca piedra that updates all the information shown in the plant database will be available very soon. But effective dosage information for the plant is already shown in the database file. As soon as the new chanca piedra book is available, it will be announced on this page:

Stay well and take care,

Leslie Taylor

Sunday, February 23, 2020

Hibiscus Flower

The first book in my new series is now available!  If you have an Amazon Kindle Unlimited account you can read it for free here: 
More information on the book is available on the Rain-Tree Publisher's page.

Additionally you can:

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Please use this blog page to comment, ask questions, discuss the many wonderful uses of Hibiscus Flowers and share your results using it.


Thursday, February 20, 2020

The Rainforest Medicinal Plant Guide Series

I am excited to present my new series of books featuring the important medicinal plants of the rainforest that I've  studied and used for more than 20 years. These new plant guides provide up-to-date factual, scientific, and vital information on how to use these powerful medicinal plants effectively to improve your health. I struggled with whether to update my big rainforest plant book, The Healing Power of Rainforest Herbs, since it really needed updating with all the new research that has been conducted on all these wonderful rainforest plants. There was just too much new information on all the plants in the book to do a second edition.  It would be huge and probably necessary to print in two volumes.

Instead, I am doing individual plant guides books on each plant. This will allow me to provide much more information on each plant, provide disease-specific dosages, and more fully explain the main uses that I recommend the plant for, and how the plant can address these uses in much greater detail. These books are between 80 to 150 pages in length.  All will be available through as both eBooks and printed books.

Keep in mind, I don't sell herbal supplements or herb products other than books. The books in this series do not promote any specific brands or herbal supplement products however, I'll share my insider information and my research on the plants in a comprehensive consumer guide to help you choose a good product, prepare it correctly, and take it in the proper dosages. These definitive medicinal plant guides concern the plants and their researched effective actions and uses. The information in these guides is more extensive, complete, and unbiased than natural product companies who sell these plants as supplements can provide.  They will contain all the information that you need to use the plants effectively which companies who sell these plants simply cannot legally provide.

The first books in this new series include:

HIBISCUS FLOWER: Nature's Secret for a Healthy Heart

Learn how to address high blood pressure, high cholesterol and clogged arteries, and more naturally without the negative side effects of prescription drugs.
More Information
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ACEROLA:  Nature's Secret to Fight Free Radicals

Discover how fighting free radicals with acerola promotes healthy aging and weight loss,  prevents many chronic diseases, and more.
Available March 2020

CAMU-CAMU: Nature's Secret for Disease Prevention

The highest source of natural vitamin C combined with the “Power of Polyphenols” in this Amazon super-fruit provides amazing health benefits
Available March 2020

CHANCA PIEDRA: Nature's Secret for Kidney Stones

Discover how to use this powerful and effective rainforest plant for kidney stones, gout, viruses, and more.
Available April 2020

GRAVIOLA: Nature's Secret for Cancer

Learn about exciting new research that reports this power plant of the Amazon may well be the most powerful natural aid in the battle against cancer. 
Available May 2020

PAU D'ARCO: Nature's Secret to Fight Infections

Learn about the infection-fighting actions of this powerful rainforest plant to kill bacteria, yeast, mold, candida, viruses, and more.
Available July 2020

CAT'S CLAW: Nature's Secret for the Immune System

Learn how to boost your immune system, reduce inflammation, and protect your brain with this effective rainforest vine.
Available June 2020

Sunday, June 30, 2019

Why Antioxidants Help You Lose Weight

I think this is my fourth blog article on antioxidants...  who knew antioxidants were that important!!

Most people have no clue that the fat in their body actually works like a metabolic organ… and it helps regulate just how easy or hard it is to lose weight and to maintain a healthy weight. If you’re overweight, it’s time to learn! Your fat may be making it much harder for you to lose weight… and causing you to fail to lose no matter what diet you try. And you probably don’t know that the solution to the problem is antioxidants!

Here’s why:

The fatty tissue in our bodies (medically called adipose tissue) is a loose connective tissue mainly composed of fat cells (medically called adipocytes). We have two different types of fatty tissues which are called brown adipose tissue (BAT) and white adipose tissue (WAT). BAT’s main function is generating heat and burning stored calories as energy in a process called thermogenesis.  That’s why BAT is often referred to as our “good fat.”  But too much of a good thing is never a good thing; even the good BAT can accumulate to high levels internally and cause problems.

WAT is the most abundant type of fat in our bodies and its main function is storing energy (and all those extra calories we eat that don’t get exercised and burned off is the “energy” we’re talking about). It’s mostly our padding layer and is found just under the skin. WAT is all the wiggly giggly stuff in our belly rolls, muffin tops, love handles and done-lops and it forms the base of that persnickety cellulite we all despise.  You might need to be from the South to know that “done-lop” is that annoying pooch of waist-WAT that “done-lops over your belt.”  WAT is basically all the fat we love to hate.   By the time you finish reading this article, you may learn to hate it even more, since it has probably been the biggest contributing factor on why it’s been so hard for you to lose weight!

WAT has been well characterized as an endocrine organ because it controls a wide range of biological functions including our metabolism. This “organ” creates a metabolic system of its own that can determine how hard or easy it is to lose weight. In addition to energy storage and heat production, fatty tissues and fat cells secrete a wide range of natural chemicals called cytokines.  These are collectively called ‘adipokines’ (adipose + cytokine).  These adipokines include pro-inflammatory protein substances as well as anti-inflammatory protein substances.  Adipokines play crucial roles in our bodies including controlling energy balance, hunger, glucose balance, immune regulation as well as creating new blood vessels, and regulating cardiac contractility just to name a few. Fat cells also produce hormone chemicals known for regulating blood pressure and fluid balance.  All in all, scientists have now discovered over 80 protein or hormone substances that are secreted by fat cells, many of which have known metabolic actions. Research has increased significantly on these natural fat-produced substances and their roles in obesity, diabetes, heart diseases and other disorders since 2010. New knowledge about these substances and their roles have encouraged the development of new drugs targeting this metabolic system in the treatment of obesity, metabolic diseases and heart conditions.

If you look at the fat of healthy lean individuals, the fat cells are small in size, fewer in number, they are insulin sensitive, and primarily secrete anti-inflammatory substances. By contrast, overweight individuals have fat cells that are large, the fat tissue is infiltrated by a large number of pro-inflammatory immune cells (called macrophages), and it secretes many more inflammatory substances and less anti-inflammatory ones. For this reason, “obese” fatty tissue is often referred to as inflamed, and obesity is now categorized as an chronic inflammatory disease. Low-grade inflammation in fatty tissue causes significant alterations or deregulations in the adipokines they secrete. Overweight and obese people live in a chronic low-level inflammatory state due to these deregulations. Since our fatty tissues and fat cells expand as we gain weight, all of these fat-secreted deregulations and resulting inflammation increases as our fat increases.  You don’t have to be obese either, just gaining some extra weight can start the process and head you down the road to deregulations.  These deregulations make it much harder to lose weight and some can make it virtually impossible to lose weight!

Why your fat might be keeping you fat

Your fat causes deregulations mainly in two ways.  Either you are secreting too many of some adipokines because you have more fat cells to make them and release them, or you aren’t secreting enough of other adipokines because the inflammation in the fat cells make it harder to produce and release them.  It’s not quite as simple as that, because the inflammation has the ability to set up self-perpetuating cycles that keep your fat sick and inflamed. So, let’s first look at fat inflammation.

Fat inflammation is created in three ways. When the fat cells do their main job of processing fats and sugars to store them in fat cells, a by-product of the process is another substance called a free radical or reactive oxygen species (ROS). The more we eat, more processing is needed and more ROS is created in the process.  ROS plays a beneficial roll in many other processes, but too much ROS is a big problem. When our built-in antioxidant system that normally controls ROS becomes overwhelmed by too much ROS, oxidative stress results and this oxidative stress causes inflammation and eventually results in cellular damage. Our fatty tissues and fat cells are very sensitive to oxidative stress and can become sick, inflamed and deregulated by not producing enough of certain adipokines as a result. It is now well documented that people who are overweight have much more ROS and oxidative stress than healthy weight people have, and the more overweight you are can directly relate to higher oxidative stress levels. But the real issue is some specific adipokines are actually doing the work of processing these molecules for storage and when there are too many or too little of these adipokines, then even more ROS can be generated and/or too much fat can be stored.

The second cause of inflammation are other ROS-like substances called advanced glycated end products, or AGEs for short.  AGEs are basically a sugar molecule that bonded to a protein molecule incorrectly. Normal sized fat cells are sensitive to insulin (which processes sugar in the diet).  The larger the fat cell grows as it stores more fat, the less sensitive it is to insulin. This interferes in how fat cells process sugar molecules and this can lead to more improper bonds and AGEs are produced. AGEs cause more ROS, can damage cells directly, and they’re well known to produce inflammation.  People who are overweight and/or obese have much higher levels of AGEs. The damage caused by AGEs (and oxidative stress) is now believed to be the leading cause of type 2 diabetes, metabolic syndrome, clogged arteries, and many heart diseases. This is why your doctor tells you to lose weight – to avoid these obesity-linked diseases because you have more ROS and AGEs than healthy weight people have.

The third cause of fat inflammation is our immune system. When injury or cellular damage occurs in our bodies it’s our immune system’s job to repair the damage or remove unrepairable cells to make room for new ones.  Many of the chemicals and cells produced by the immune system are pro-inflammatory; inflammation is a natural immune response.  When fat cells are damage by oxidative stress and AGE’s the immune system can flood the fatty tissues with these inflammatory chemicals and it triggers some of the pro-inflammatory adipokines to increase in number. In fact, some of the cells that make up the immune system are, in fact, adipokines. Part of our immune system lives in our fat.  The result is a lot more inflammation in our fat which has a deregulating effect and inflammation can cause more ROS. This is why sick deregulated “obese” fat produces more pro-inflammatory adipokines and less anti-inflammatory ones – the immune system is driving this deregulation trying to repair damaged fat cells.

There are just too many adipokines that become deregulated in this process to explain them all, so we’ll look at just two as examples.  These two adipokines have a well-known effect on how hard or easy it is to maintain a healthy weight. These are also good examples how deregulations cause some vicious cycles between deregulation, oxidative stress and inflammation and keeps your fat, keeping you fat.  The first is an adipokine called leptin and it’s a good example of too much fat producing and releasing too much of an adipokine.
One of leptin’s main roles is controlling appetite which helps determines how much we eat. As our fat expands, we actually produce more and more leptin, which you’d think would be a good thing.  Unfortunately, it isn’t.  Just like too much sugar causes too much insulin which results in insulin resistance, too much leptin produced by too much fat promotes leptin resistance. Chronic inflammation also helps create leptin resistance and too much leptin also produces more inflammation. Leptin is actually one of those pro-inflammatory adipokines. Most obese people are leptin resistant, and even being moderately overweight can result in leptin resistance. Once we lose leptin resistance, we can stay hungry all the time and we usually eat more than we really need to and it make eating less when dieting much harder. Moreover, leptin plays a role in how proteins, sugars and fat molecules are processed right before storage in fat cells.  This means too much leptin can result in better/more processing and more molecules/calories are stored as fat in these cells instead of burned as energy.  Leptin also plays a role in the immune system as it participates in the activation of immune cells called monocytes and macrophages which can invade the fatty tissues and cause inflammation and the generation of more ROS. Do you see the self-perpetuating cycle here and how this one adipokine can make weight gain easier and weight loss harder as the inflammation, ROS, and immune system go round and round?  Not to mention it makes you hungrier and stores more fat!  Wow, huh?

The next example is an adipokine named adiponectin and it is a good example of  fat cells under the stress of inflammation not producing and releasing enough of an adipokine.  Adiponectin is the most abundant adipokine produced in our fat cells and it is one of the anti-inflammatory substances produced in our fat. When our fat tissues and cells come under oxidative stress and inflammation, adiponectin levels are greatly reduced. Adiponectin levels are decreased in people with obesity, insulin resistance, and type 2 diabetes (all of which have much higher levels of ROS, AGE’s and resulting inflammation), Adiponectin helps break down and metabolize fats and sugars in the liver and exerts insulin-sensitizing, anti-inflammatory, and immune modulating actions. If our fat cells and other cells start losing insulin sensitivity, the lack of adiponectin (and three other adipokines) are playing a role. Don’t forget, insulin resistance leads to more AGEs being formed and more AGEs means more inflammation and ROS!
Just looking at just these two adipokines reveal the deregulations that can occur when we begin gaining weight. By the very nature of how these two work, and what kinds of roles they play, gives us a better understanding how deregulated fat begins to  keep us fat and promote more weight gain. However, don’t forget, our fat is producing over 80 different adipokines playing many roles and these are just two! Much more is going on in our fat that isn’t being discussed here, much of which are now shown to be leading causes of chronic diseases.  The self-perpetuating cycles between the immune system response to AGEs, oxidative stress and cellular damage by ROS are all maintaining a chronic inflammatory state which keep these deregulations settled into a “new normal” state for people who are overweight. Losing weight with all these deregulations isn’t easy.

The MUCH easier way to lose weight is to treat the deregulations by treating the inflammation first. This represents a brand-new and effective weight loss strategy that many people just don’t know about yet.  Drug researchers know however; some creative drug companies are re-evaluating their anti-inflammatory drugs as possible candidates to re-brand into new weight loss drugs. They know relieving inflammation in the fat will create weight loss by fixing some of these deregulations. If it weren’t for those pesky side effects of some of their drugs being used long term… and they’d need to be used long term, since they aren’t addressing the actual cause of the inflammation.
That’s where natural antioxidants come in!  In fact, most every natural antioxidant plant chemical has also shown to be anti-inflammatory. In many cases, it is actually relieving inflammation by reducing oxidative stress. Some rainforest plants I’ve been studying also have antioxidants that also reduce the formation of AGEs. Reducing AGES, ROS, and the resulting oxidative stress and cell damage will cool off the immune system and all of the inflammation by all of these causes will abate. This addresses one of the root cause of weight gain and it will help you fix the deregulations that have been silently working against you and making it harder to lose weight.

Stay tuned for more… I’ll be uploading a new plant in the online plant database soon that has human studies on both weight loss and its strong antioxidant actions.  I’m currently rewriting a database file on an existing rainforest plant with new studies on weight loss and it too is a strong antioxidant!   It’s some exciting information that I think will help lots of people not only lose weight; it will help them maintain their new weight much easier as well! All this new information makes developing a new rainforest antioxidant formula much more important, and I’m working on that one too!

Friday, March 1, 2019

The Safety of Graviola

Every couple of years someone publishes a research paper saying graviola causes neurotoxicity or the main anticancer chemical, annonacin, is a neurotoxin and it’s unsafe to take graviola supplements. I’m going to share my personal experience and provide you with my educated opinion of these studies and let you decide for yourself whether graviola is dangerous to take.  These are my opinions only, based on my research and my personal experience… do with it what you will and make your own decisions about your own health.

I’m writing this quickly without going back to completely review all these old studies. I just don’t have the time right now, so am going to summarize. The very first study reporting the neurotoxicity of graviola extracted graviola in methanol or ethanol (don’t remember which) and injected directly into some lab animals’ brains (mice or rats). This study reported graviola was a neurotoxin because it caused cell death in the brain. At the time, I said okay… my customers buying graviola weren’t injecting their supplements into their brain, so no worries.  I knew lots of stuff, even just the methanol, would cause cell death if it were directly injected into the brain. I also knew this certainly did NOT prove graviola could make it over the blood-brain barrier into the brain in the same fashion when it was ingested orally.

Then this isolated, economically disadvantaged community in the West Indies (Guadeloupe) came down with some unexplained Parkinson’s Disease-like symptoms (trembling, shaking, tics, etc.). They were interviewed about what was in their diet, looking for what that might be a dietary/environmental cause. Like most people in the tropics, graviola fruit was in their diet, and they also used a graviola leaf tea as an herbal remedy occasionally when needed. They weren’t eating or drinking both daily. The researchers assumed (or wanted to believe) it was the graviola because of the previous “neurotoxic” study which injected graviola into the brain. They did another study “to prove it,” this time injecting just a graviola chemical called annonacin into the brains of lab animals. They again reported cell death, especially to certain dopamine-type brain cells which might possibly cause  some of the same sort of symptoms (lack of dopamine causes/worsens Parkinson’s). In this study they reported graviola causes Parkinson’s-like symptoms because it has neurotoxic compounds and cautioned people not to take it. They, of course, never determined graviola compounds and annonacin specifically were actually in the brains of these people or proved it was graviola that caused their shaking – it was still just a correlation or possible link based on a dietary questionnaire when they published this study.

A while later is was determined that the diet of these people were nutritionally deficient and that was the cause of their symptoms. I think is was several of the B vitamins severely lacking, but won’t take the time to go back and look it up. They cured these people of their Parkinson’s-like symptoms by fixing the nutritional deficiency (not by removing graviola from their diets). But for years, graviola was attributed with this incorrect link and a warning that graviola might cause Parkinson’s-like symptoms because of “possible neurotoxicity.” I’m STILL seeing this incorrect association in some of the research they’ve continued to publish trying to somehow prove graviola is somehow unsafe and is neurotoxic and the science gets even more convoluted trying to prove this concept.

Convoluted? My opinion of course, but let me give you an example. In 2015 they published a research paper that reported: “These results demonstrate that the intake of dietary supplements containing plant material from Annonaceae may be hazardous to health in terms of neurotoxicity.” Based on what? On an in vitro (test tube) study. First, they extracted 3 different Anonna plants (including graviola) in hot, pressurized, ethyl acetate (a toxic, flammable chemical you have to wear protective equipment to handle) Logically, nothing like what happens when you take some leaf capsules or leaf tea by mouth and it goes through digestion, right? What gets “extracted” in your stomach logically isn’t what gets extracted under heat and pressure in a toxic chemical that’s found in your nail polish remover that strips polymers off your nails. Right? Logically, speaking of course.

Then they put some “brain cells” in some little cup holders/wells. But they didn’t really use brain cells, they used “Lund human mesencephalic neurons.” You purchase these from a lab that grows them and sells them for research purposes. These are actually undeveloped, precursor brain cells that came from an 8 week old human embryo/fetus. Logically, these cells are not present in your brain or mine, and I’m assuming they’d be a tad more delicate than a fully formed brain cell. That’s an assumption, I haven’t bothered to look it up. So, they mixed these fetal precursor cells directly with this toxic-nail-polisher-remover graviola extract in the little cup holders, waited 48 hours and said: “Wow, this extract killed 67% of these delicate precursor cells!” Therefore, Annona plants are neurotoxic and taking a graviola/Annona supplement is harmful for you to take. Huh? Wait. What?

Personally, I’m not worried that what I eat or drink is going to be digested and extracted in the same manner as they extracted it. I won’t be washing my supplements down with nail polish remover either. I don’t logically think it will be absorbed in my bloodstream thru normal digestion in the same manner and somehow make it thru my blood-brain barrier meant to keep most things out of my brain.  I don’t logically think it will come in direct contact with my brain cells like it did in the little cup holders and have the same effect they demonstrated in this study. But hey, that’s me. I’m way logical, and now that you have the facts about this study, you can draw your own conclusions.

I think if I sold about a million bottles of graviola supplements over 15 years (which I did) and was killing 67% of my customer’s brain cells in one dose, someone would have said something. They didn’t, and graviola didn’t. Also, never once, did we get any report of anyone taking these supplements having Parkinson’s-like symptoms. Not one. And the next study they published a year later proved it.

This one was just as convoluted in my personal opinion, but I need to discuss it because it refutes all prior studies of brain cell death/toxicity. Again, you can decide yourself. This time, they went in the lab to prove that long-term daily consumption of graviola fruit juice causes neurotoxicity. I’m just assuming graviola juice products had gained in popularity enough to target this then. But they didn’t use regular, normal mice for the study. They used mice that carried a genetic mutation in the brain which causes a weaker blood-brain barrier and the inability to clear out substances from the brain once it gets in the brain so it has a build-up/residual effect. This genetic mutation isn’t very common in humans and is present in a very small percentage of people, living mostly in Northern Europe and Japan. The mutation also creates more of a brain protein called tau. They justified using these mutated mice because MAYBE the nutritional deficiency in the West Indians could have POSSIBLY created a similar condition (weakened brain barrier and/or inability to clear substances from the brain) but this was never confirmed in the actual patients who had Parkinson’s symptoms who were cured by just fixing the nutritional deficiency. Convoluted? You decide. What I see in reading thousands of studies, is that researchers can easily set up their study protocols to prove exactly what they want to prove before the study even starts. Just my opinion, of course.

So, they gave one group of the mutated mice only graviola fruit juice to drink instead of water for an entire year. (!) Won’t take the time to go there. (sigh) They gave another group of mutated mice water to drink instead and compared the groups. The lifespan of a normal mouse is about 5 years (I haven’t bothered to looked up the lifespan of these mutated mice) but that would be about the equivalent of a human drinking nothing but graviola fruit juice instead of water for like 10 years or more. (Which of course, I would never do and you shouldn’t either.) If I believed the previous study of killing 67% of their brain cells with one dose, I would have assumed these mice wouldn’t have made it a year. But they did, and when they examined their brains after a year of this chronic use, there was no cell death in the brain, no astrocyte cell loss, no loss/death of dopamine-type cells or any of the other cell death claimed in all the other studies (that manipulated graviola or its main annonacin compound over the blood-brain barrier in some fashion – just as this study manipulated it over the barrier with the mutated gene causing a weakened barrier).

None. Nada. Zip. They also didn't see any "Parkinson's-like symptoms" in these mice (even the mutated mice) for the entire year the mice drank the graviola fruit juice.  What it did do was aggravate the genetic problem of too much tau (that isn’t present in MY brain) and caused some pro-oxidant damage to the excessive tau in their brains. There was also a little bit of oxidation in the non-mutated mice’s tau but no-where near the mutated ones. This oxidation, in my personal opinion, could possibly be related to drinking only fruit juice (any kind of fruit juice) instead of water for like 10 years, which might just cause some oxidative free radicals. Who would do that? Not me. This oxidation could also have been the chronic buildup (mutated barrier) and effect of the three chemical preservatives in the fruit juice these mice drank too. Again, if I have to say it, you shouldn’t do this either. Water is good for you; drink lots! Chemical preservatives can be bad for you; avoid them when you can and don’t take them chronically like that.

Several other studies have been published over the years about graviola and neurotoxicity but they were injecting graviola extracts (which contained various toxic extracting liquids) or just the isolated annonacin directly into the bloodstream (intravenously) to get it over the blood-brain barrier. One study even put it in one of those chemo or pain medication drug pumps that pumped it into the bloodstream continuously over 3 days. Some injected it under the skin or in the muscles, like a regular shot would. These studies all claimed neurotoxicity to various brain cells in their published research by manipulating the method to help get it over the blood-brain barrier. Again, nothing like what happens when someone drinks a tea, takes a capsule, or drinks some juice and it goes through the normal digestion process. And this mutated mouse study confirms the neurotoxicity these studies reported simply doesn’t happen when the leaf or juice is ingested (not injected).  They also proved the long-term consumption of graviola fruit juice does NOT cause Parkinson's-like symptoms in mice.

But studies still keep getting published that it does and that graviola is a neurotoxin. I won’t go there on why I think they are. Let’s just acknowledge they are and leave it at that.

One recent study again reporting neurotoxicity I read yesterday made me laugh out loud. Researchers have this mutated flat worm they use to determine if a plant or plant compound might be “anti-aging.” This worm is mutated in a special way, so that if you can prolong the short life of this worm with some compound or plant, it indicates you might possibly prolong the life of humans. I’ve seen a lot of this research using this worm on the Amazon plants I’m updating since it targets possible anti-aging compounds for further research. Anti-aging plants/chemicals/products/supplements are of great interest to researchers these days. Anyway, they exposed these mutated worms to a graviola extract. They produced about 20% fewer eggs and didn’t wiggle around quite as much. They said this was because graviola was “probably neurotoxic.” [insert laughter here] Graviola is used as an insecticide and it’s a documented antiparasitic (against various worms); I was shocked graviola didn’t kill these wigglers and wondered just how they had mutated them!! Before I found out about graviola and cancer, my main use of graviola was as an ingredient in my herbal remedy to kill parasites and worms. Several new studies continue to report that graviola can kill intestinal worms and parasites in animals and humans. 

So, let me summarize. The way I personally avoid all the documented/researched/published "brain toxicity" from graviola is: A.) I don’t extract it (especially in toxic liquids) and inject it into my brain. B.) I don’t go thru a complicated process to just extract annonacin from graviola and inject that in my brain either. C.) I never ever inject graviola or annonacin in any form directly into my veins or under my skin, or in my muscles either (or put it in a “pain-pump” to inject it into my bloodstream regularly over many days at a time). D.) And I never ever use or take graviola chronically every day. I am going to tell you why in another blog because I know some people are doing this. Go here to see why I think it isn’t necessary or helpful to do so. And btw, if I have to say it, I would advise you to not do A thru C above either. Sheesh!

I should probably take the time to remind everyone; graviola is a popular fruit in Brazil and throughout Latin America. The fruit is sold in markets and grocery stores, fresh and canned fruit juices are widely sold and the fruit is often prepared in ice creams, syrups, candy, shakes and other beverages. I can even find standard graviola fruit juice at my grocery store in Texas sold under the Spanish name, Guanabana with the rest of the canned fruit juices and nectars (unfortunately loaded with high fructose corn syrup).  Outside of the one isolated case in the West Indies that was proven to NOT be graviola, there has not been any outbreak of Parkinson's Disease, or Parkinson's-like symptoms any where in Brazil, Latin America or North America, for that matter, where graviola supplements have steadily gained in popularity.  An search I just did, linked to 542 products searching for "graviola supplements."

So, these are my personal opinions; you can do with them what you will and make your own personal choices about your health. Look up these studies on PubMed and read them like I did and form your own opinions about them. I haven’t shown any of the neurotoxic studies in graviola’s plant database file either for all the obvious reasons I’ve discussed. I believe these studies just aren’t applicable to how graviola is used as an herbal supplement today which is what my online plant database is about.

As always, stay tuned! More to come… Don’t forget to read why I personally don’t use graviola chronically/daily or for “wellness”“cancer prevention” or “immune health.”

Welcome to Leslie Taylor's New Blog

Hello! My name is Leslie Taylor and I am the founder of Raintree Nutrition, Inc ., a company that was a leader in creating a world-wid...